Publisher Correction: Assessing spatial pattern separation in rodents using the object pattern separation task
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چکیده
منابع مشابه
Running enhances spatial pattern separation in mice.
Increasing evidence suggests that regular exercise improves brain health and promotes synaptic plasticity and hippocampal neurogenesis. Exercise improves learning, but specific mechanisms of information processing influenced by physical activity are unknown. Here, we report that voluntary running enhanced the ability of adult (3 months old) male C57BL/6 mice to discriminate between the location...
متن کاملBrief Communication Visual object pattern separation varies in older adults
Visual object pattern separation varies in older adults Heather M. Holden, Chelsea Toner, Eva Pirogovsky, C. Brock Kirwan, and Paul E. Gilbert San Diego State University–University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California 92120, USA; Department of Psychology, Department of Psychiatry, San Diego State University, San Diego, California 92182, US...
متن کاملPattern Completion and Pattern Separation Mechanisms in the Hippocampus
There is great interest in how pattern separation and pattern completion in the hippocampus contribute to its functions in memory and spatial function (Giocomo et al. 2011; Jezek et al. 2011; Leutgeb et al. 2007; McHugh et al. 2007; Nakashiba et al. 2012; Nakazawa et al. 2002, 2003; Wills et al. 2005), and among those who have made many contributions in this area are Ray Kesner and his colleagu...
متن کاملRunning Improves Pattern Separation during Novel Object Recognition
Running increases adult neurogenesis and improves pattern separation in various memory tasks including context fear conditioning or touch-screen based spatial learning. However, it is unknown whether pattern separation is improved in spontaneous behavior, not emotionally biased by positive or negative reinforcement. Here we investigated the effect of voluntary running on pattern separation duri...
متن کاملReassessing pattern separation in the dentate gyrus
INTRODUCTION The dentate gyrus (DG) is postulated to be a “pattern separator” (Marr, 1971; Rolls, 1989a,b, 1990; Treves and Rolls, 1994). Yet, the definition of pattern separation has become a haze, with researchers using the term interchangeably to describe computational processes, changes in cell ensemble activity, and even behavioral phenomena (Leutgeb et al., 2007; McHugh et al., 2007; Clel...
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ژورنال
عنوان ژورنال: Nature Protocols
سال: 2018
ISSN: 1754-2189,1750-2799
DOI: 10.1038/s41596-018-0061-2